What defense strategies can be used to detect or prevent IE simulation-based file downloads?

Defense strategies include monitoring for unusual `iexplore.exe` process launches (e.g., from non-IE parent processes like `powershell.exe`), tracking COM object instantiation of `InternetExplorer.Application`, and auditing scheduled tasks or services that start IE. Additionally, enabling application whitelisting with behavior analysis and inspecting cache directories for unexpected files can help. The article concludes with a summary of these defenses, emphasizing the need to detect both active and passive exploitation methods.